A new paper in
Oxford Open Immunology, published by Oxford University Press, examines prior findings in the field of neuroimmunology that suggest potential treatment strategies for patients suffering long-term symptoms from COVID-19.
Though COVID-19 was initially believed to be a short-term illness, lasting between one and three weeks, it s clear that a substantial number of patients will experience symptoms beyond that, with some patients suffering from health problems for more 12 weeks. In fact, for patients who were initially hospitalized, more than 80% reported at least one symptom that persisted beyond the first month.
The symptoms of long-COVID can vary widely, including cough, low grade fever, fatigue, chest pain, shortness of breath, headaches, cognitive difficulties, muscle pain and weaknesses, gastrointestinal distress, rashes, metabolic disruption, depression and other mental health conditions. In the context of other disorders and syndromes, these symptoms appear to
The product portfolio includes lamotrigine (ET-105), zonisamide (ET-104), and topiramate (ET-101). These medications are currently under review with the FDA.
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New research from Trinity College Dublin suggests that older adults can be more focused, less impeded by anxiety and less mentally restless than younger adults. The team at the Trinity College Institute of Neuroscience (TCIN) (today, Wednesday, 10th February, 2021) show that older adults appear to mitigate the negative aspects of cognitive decline by increasing motivation and adopting more efficient strategies to suspend the wandering mind when focus is required.
The study, published in the journal
Psychology and Aging (American Psychological Association) is the first to adjudicate between competing theories of age-related mind-wandering dominant in the field. It highlights the influential roles of affective and motivational factors in driving age-related differences in unintentional mind-wandering and provide reasons to be less persuaded by previous cognitive resources accounts.
Researchers at the University of Tsukuba report two areas of the monkey brain that represent expected value when making economic decisions. Analyses showed that neuronal activity in the VS and the cOFC provided stable representations of expected value, while other regions that are part of the reward network in the brain did not. State-space analysis revealed that the way expected value was represented over time differed in these two areas.
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IMAGE: Neural plasticity, the remarkable ability of the brain to modify and reorganize itself at the synapse, circuit and cellular levels is affected by and/or in response to excessive alcohol intake. view more
Credit: Steven P. Guerin
Amsterdam, NL, February 10, 2021 - Neuroplasticity, the remarkable ability of the brain to modify and reorganize itself, is affected by or in response to excessive alcohol, whether through individual consumption or exposure in the womb. It is now well accepted that the birth and integration of new neurons continue beyond development and into adulthood. New discoveries and insights on how alcohol impacts this and other plastic processes are discussed in Alcohol and Neural Plasticity, a special issue of